GT Metabolic™ Magnetic Anastomosis System

GT Metabolic has developed and is ready to launch a proprietary magnetic compression anastomosis technology.1 The incisionless, sutureless, staple-free technique1-4 is designed to revolutionize how surgeons achieve anastomosis.

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Technique Used In Clinical Studies1-3:

Magnetic System Side-to-Side Compression Anastomosis Duodeno-ileostomy

Step 1

The patient swallows the first magnet in the outpatient
department. The magnet travels into the stomach and
the duodenum and reaches the ligament of Treitz in
about two hours.

Step 2

Once the patient is under anesthesia in the OR, a
marker is placed in the ileum 250cm from cecum
laparoscopically.

Step 3

The laparoscopic positioning device (LPD) is used to
capture the magnet and direct it distally through the
jejunal lumen to the marked position in the ileum, 250
cm from the ileocecal valve.

Step 4

At the same time, the second magnet is transported
orogastrically by a flexible endoscopic catheter into the
antrum and then is brought into the duodenum ~2cm
after the pylorus. This is the intended magnet fusion
site

Step 5

The distal magnet in the ileum is elevated antecolic
and brought together with the second magnet in the
post-pyloric duodenum.

Step 6

The second (proximal) magnet is released to self-align
with the first (distal) magnet through the intestinal
walls. The endoscope and LPD are withdrawn.
Peterson’ s defect is closed.

Step 7

In several days, the two magnets are fully fused after
compressing and sloughing the tissue between them.
The magnets detach several weeks later from the
duodeno-ileal site and are expressed naturally.

Step 8

Food flows through the duodenal lumen, and also through the patent anastomosis into the ileal lumen. The anastomosis is extremely durable after 3-4 weeks. 1,3

Step 9

After the procedure, patients are carefully monitored with special attention to hemodynamic conditions and cardiac rhythm for a minimum of 24 hours. Successful placement of the MAGNET System is confirmed radiologically by abdominal x-ray, and fluoroscopically, using barium or gastrographin on postoperative day 1. Patients meet with a dietician or nutritionist prior to discharge to review the post-procedure diet. 1,3

Surgeon Early Observations

Product Technology

These videos include references to the use of a surgical device and the opinions of the individual presenter. The videos may also include references to medical devices still in development or available for investigational use only and represents scientific exchange.

GT Metabolic™ Mag DI™ System

MAGDI™
MAGNET

  • A 40mm Parylene-C coated
    neodymium magnet is encased
    in a Titanium shell with a PGLA
    bio-fragmentable flange.
  • A delivery system connect/release
    mechanism is located at one end of
    the magnet.
  • Device is intended for use for
    side-to-side duodeno-ileal
    anastomosis in minimally invasive
    and laparoscopic surgery.
  • Sterile; disposable.

MAGDI™
DELIVERY SYSTEM

  • The delivery system is a disposable
    flexible orogastric delivery catheter
    198cm in length that attaches to the
    linear MagDI magnet for placement
    and positioning.
  • The proximal end of the catheter
    consists of a ring handle pull trigger
    for easy deployment of the magnet.
  • The delivery system catheter must
    be paired with a flexible endoscope
    with a working channel of at least
    2.8mm or greater.
  • Sterile; disposable.

MAGDI™ LAPAROSCOPIC POSITIONING DEVICE

  • 41cm long reusable laparoscopic
    positioning device (LPD) is
    compatible with a 12mm trocar.
  • Instrument is comprised of a
    Paralene-C coated neodymium
    magnet encased in a titanium
    housing, non-magnetic shaft and
    positioning handle detailing the
    strength of the instrument.
  • Offered in five magnetic strengths,
    the LPD provides surgeon with
    options depending on patient’s
    bowel morphology. (A higher number
    indicates greater magnetic strength.
  • LPD is used to position the linear
    magnetic technology (LMT) at the
    desired anastomotic site.
  • Reusable; requires sterilization.
View Product Detail Sheet

The Founders of Our Technology

GT Metabolic founders Thierry Thaure and Michel Gagner, MD, are renowned global experts in the area of bariatric and metabolic procedures. They’ve led the GT Metabolic team in engineering a magnetic compression solution called delayed anastomosis technology (DAT) that surgeons can use to create consistent anastomosis while helping minimize potential complications.1-4

VIEW FULL LEADERSHIP TEAM
Thierry Thaure
CEO & Co-founder
Michel Gagner, MD
CMO & Co-founder

1. De Novo marketing authorization DEN240013. MagDI™ System for side-to-side duodeno-ileal anastomosis granted De Novo marketing authorization from the U.S. Food and Drug Administration (FDA). 2 July 2024.

2. Gagner, M., Almutlaq, L., Cadiere, G.-B., Torres, A. J., Sanchez-Pernaute, A., Buchwald, J. N., & Abuladze, D. (2023). Side-to-side magnetic duodeno-ileostomy in adults with severe obesity with or without type 2 diabetes: Early outcomes with prior or concurrent sleeve gastrectomy. Surgery for Obesity and Related Diseases. https://doi.org/10.1016/j.soard.2023.10.018

3. Gagner, M., Abuladze, D., Koiava, L. et al.First-in-Human Side-to-Side Magnetic Compression Duodeno-ileostomy with the Magnet Anastomosis System. OBES SURG 33, 2282–2292 (2023). https://doi.org/10.1007/s11695-023-06708-x

4. Gagner M, Cadiere GB, Sanchez-Pernaute A, Abuladze D, Krinke T, Buchwald JN, Van Sante N, Van Gossum M, Dziakova J, Koiava L, Odovic M, Poras M, Almutlaq L, Torres AJ. Side-to-side magnet anastomosis system duodeno-ileostomy with sleeve gastrectomy: early multi-center results. Surg Endosc. 2023 Aug;37(8):6452-6463. doi: 10.1007/s00464-023-10134-6. Epub 2023 May 22. PMID: 37217682; PMCID: PMC10202352.

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