GT Metabolic™ Magnetic Anastomosis System

GT Metabolic has developed and is ready to launch a proprietary magnetic compression anastomosis technology.1 The incisionless, sutureless, staple-free technique1-4 is designed to revolutionize how surgeons achieve anastomosis.

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Technique Used In Clinical Studies1-3:

Magnetic System Side-to-Side Compression Anastomosis Duodeno-ileostomy

Step 1

Under general anesthesia, laparoscopically, a marker is placed in the ileum 250 cm from the cecum. 1-3

Step 2

A retrievable metal bowel clamp is placed 10-15 cm distal to the ligament of Treitz. 1-3

Step 3

The first (distal) magnet is transported orogastrically by flexible endoscopic catheter to the fourth part of the duodenum. The magnet is released in the proximal jejunum and is attracted toward the clamp. 1,3,4

Step 4

A positioning device is used to grasp the magnet, the clamp is removed, and the positioner directs the magnet through the jejunal lumen to the marked position in the ileum, 250 cm from the ileocecal valve. The endoscope is retracted to the level of the stomach. 1,3

Step 5

The first (distal) magnet in the ileum is elevated over the transverse colon with two non-magnetic bowel forceps and brought anterior and latero-lateral to the post-pyloric duodenum. The second (proximal) magnet is delivered through the endoscope to the intended magnet fusion site in the post-pyloric duodenum. 1,3

Step 6

The second (proximal) magnet is released to self-align with the first (distal) magnet through the intestinal walls. The endoscope and magnet positioning device are withdrawn. Petersen’s defect is closed. 1,3

Step 7

In several days, the two magnets are fully fused after compressing and sloughing the tissue between them. The magnets detach several weeks later from the duodeno-ileal site and are expressed naturally. 1-3

Step 8

Food flows through the duodenal lumen, and also through the patent anastomosis into the ileal lumen. The anastomosis is extremely durable after 3-4 weeks. 1,3

Step 9

After the procedure, patients are carefully monitored with special attention to hemodynamic conditions and cardiac rhythm for a minimum of 24 hours. Successful placement of the MAGNET System is confirmed radiologically by abdominal x-ray, and fluoroscopically, using barium or gastrographin on postoperative day 1. Patients meet with a dietician or nutritionist prior to discharge to review the post-procedure diet. 1,3

Surgeon Early Observations

Product Technology

These videos include references to the use of a surgical device and the opinions of the individual presenter. The videos may also include references to medical devices still in development or available for investigational use only and represents scientific exchange.

The Founders of Our Technology

GT Metabolic founders Thierry Thaure and Michel Gagner, MD, are renowned global experts in the area of bariatric and metabolic procedures. They’ve led the GT Metabolic team in engineering a magnetic compression solution called delayed anastomosis technology (DAT) that surgeons can use to create consistent anastomosis while helping minimize potential complications.1-4

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Thierry Thaure
CEO & Co-founder
Michel Gagner, MD
CMO & Co-founder

1. De Novo marketing authorization DEN240013. MagDI™ System for side-to-side duodeno-ileal anastomosis granted De Novo marketing authorization from the U.S. Food and Drug Administration (FDA). 2 July 2024.

2. Gagner, M., Almutlaq, L., Cadiere, G.-B., Torres, A. J., Sanchez-Pernaute, A., Buchwald, J. N., & Abuladze, D. (2023). Side-to-side magnetic duodeno-ileostomy in adults with severe obesity with or without type 2 diabetes: Early outcomes with prior or concurrent sleeve gastrectomy. Surgery for Obesity and Related Diseases. https://doi.org/10.1016/j.soard.2023.10.018

3. Gagner, M., Abuladze, D., Koiava, L. et al.First-in-Human Side-to-Side Magnetic Compression Duodeno-ileostomy with the Magnet Anastomosis System. OBES SURG 33, 2282–2292 (2023). https://doi.org/10.1007/s11695-023-06708-x

4. Gagner M, Cadiere GB, Sanchez-Pernaute A, Abuladze D, Krinke T, Buchwald JN, Van Sante N, Van Gossum M, Dziakova J, Koiava L, Odovic M, Poras M, Almutlaq L, Torres AJ. Side-to-side magnet anastomosis system duodeno-ileostomy with sleeve gastrectomy: early multi-center results. Surg Endosc. 2023 Aug;37(8):6452-6463. doi: 10.1007/s00464-023-10134-6. Epub 2023 May 22. PMID: 37217682; PMCID: PMC10202352.

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